C14orf166 Antikörper (AA 151-244) (Biotin)

Produktnummer ABIN717418

Produktdetails anti-C14orf166 Antikörper (Biotin)

Target: C14orf166 (Chromosome 14 Open Reading Frame 166 (C14orf166))

Bindungsspezifität: AA 151-244

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C14orf166 Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RLLM1/C14orf166

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu C14orf166

Target: C14orf166 (Chromosome 14 Open Reading Frame 166 (C14orf166))

Andere Bezeichnung: RLLM1 (C14orf166 Produkte)

Synonyme: CGI99 antikoerper, CLE antikoerper, CLE7 antikoerper, LCRP369 antikoerper, RLLM1 antikoerper, C14orf166 antikoerper, C10H14orf166 antikoerper, RNA transcription, translation and transport factor antikoerper, chromosome 5 C14orf166 homolog antikoerper, RNA transcription, translation and transport factor S homeolog antikoerper, zgc:56576 antikoerper, RTRAF antikoerper, C5H14orf166 antikoerper, rtraf.S antikoerper, zgc:56576 antikoerper

Hintergrund:

Synonyms: CGI 99, CGI99, CLE, Homeobox prox 1, RLLM1, Chromosome 14 open reading frame 166, CLE7, LCRP369, RLL mot containing 1, CN166_HUMAN.

Background: CGI-99 is a 244 amino acid protein that localizes to the nucleus, as well as to the cytoplasm, and belongs to the UPF0568 family. Expressed in a variety of tissues with particularly high levels in heart and skeletal muscle, CGI-99 functions as a homodimer that interacts with Ninein and is thought to regulate Ninein function. CGI-99 is overexpressed in brain tumor tissue, suggesting a role in tumor development and metastasis. The gene encoding CGI-99 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Gen-ID: 51637