PDE12 Antikörper (AA 17-300)

Produktnummer ABIN7269299

Produktdetails anti-PDE12 Antikörper

Target: PDE12 (Phosphodiesterase 12 (PDE12))

Bindungsspezifität: AA 17-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: PDE12 Rabbit pAb

Sequenz: AVEKLSRAEA GSQTAAGAME RAVVRCVPSE PKLSLSFALA DGSHKNMQRD QSEPLGRVLS RIATNALKGH AKAAAAKKSR KSRPNASGGA ACSGPGPEPA VFCEPVVKLY YREEAVAEDV LNVDAWQDGA VLQIGDVKYK VERNPPAFTE LQLPRYIMAG FPVCPKLSLE FGDPASSLFR WYKEAKPGAA EPEVGVPSSL SPSSPSSSWT ETDVEERVYT PSNADIGLRL KLHCTPGDGQ RFGHSRELES VCVVEAGPGT CTFDHRHLYT KKVTEDALIR TVSY

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-300 of human PDE12 (NP_001309106.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PDE12

Target: PDE12 (Phosphodiesterase 12 (PDE12))

Andere Bezeichnung: PDE12 (PDE12 Produkte)

Synonyme: 2'-PDE antikoerper, E430028B21Rik antikoerper, LRRGT00074 antikoerper, RGD1310975 antikoerper, phosphodiesterase 12 S homeolog antikoerper, phosphodiesterase 12 antikoerper, pde12.S antikoerper, PDE12 antikoerper, pde12 antikoerper, Pde12 antikoerper

Hintergrund: Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs. Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells and Hela cells.,PDE12,2-PDE,PDE12

Gen-ID: 201626

UniProt: Q6L8Q7