PGAM5 Antikörper (AA 30-225)

Produktnummer ABIN7269317

Produktdetails anti-PGAM5 Antikörper

Target: PGAM5 (Phosphoglycerate Mutase Family Member 5 (PGAM5))

Bindungsspezifität: AA 30-225

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGAM5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Verwendungszweck: PGAM5 Rabbit pAb

Sequenz: KPRAGGDAEP RPAEPPAWAG GARPGPGVWD PNWDRREPLS LINVRKRNVE SGEEELASKL DHYKAKATRH IFLIRHSQYH VDGSLEKDRT LTPLGREQAE LTGLRLASLG LKFNKIVHSS MTRAIETTDI ISRHLPGVCK VSTDLLREGA PIEPDPPVSH WKPEAVQYYE DGARIEAAFR NYIHRADARQ EEDSYE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-225 of human PGAM5 (NP_612642.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PGAM5

Target: PGAM5 (Phosphoglycerate Mutase Family Member 5 (PGAM5))

Andere Bezeichnung: PGAM5 (PGAM5 Produkte)

Hintergrund: Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.,PGAM5,BXLBV68,Signal Transduction,PGAM5

Molekulargewicht: 28kDa/32kDa

Gen-ID: 192111

UniProt: Q96HS1