Melanoma gp100 Antikörper (AA 25-300)
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- Target Alle Melanoma gp100 (PMEL) Antikörper anzeigen
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
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Bindungsspezifität
- AA 25-300
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Melanoma gp100 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Western Blotting (WB)
- Verwendungszweck
- PMEL Rabbit pAb
- Sequenz
- KVPRNQDWLG VSRQLRTKAW NRQLYPEWTE AQRLDCWRGG QVSLKVSNDG PTLIGANASF SIALNFPGSQ KVLPDGQVIW VNNTIINGSQ VWGGQPVYPQ ETDDACIFPD GGPCPSGSWS QKRSFVYVWK TWGQYWQVLG GPVSGLSIGT GRAMLGTHTM EVTVYHRRGS RSYVPLAHSS SAFTITDQVP FSVSVSQLRA LDGGNKHFLR NQPLTFALQL HDPSGYLAEA DLSYTWDFGD SSGTLISRAL VVTHTYLEPG PVTAQVVLQA AIPLTS
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 25-300 of human PMEL (NP_008859.1).
- Isotyp
- IgG
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anti-Premelanosome Protein (PMEL) antibody
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anti-Premelanosome Protein (PMEL) (C-Term) antibodyVerified PMEL Reaktivität: Human, Maus IF, WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Premelanosome Protein (PMEL) (N-Term) antibodyPMEL Reaktivität: Human, Pferd, Ratte, Maus, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Ziege IHC, WB Wirt: Kaninchen Polyclonal unconjugated
anti-Premelanosome Protein (PMEL) (AA 25-467) antibodyPMEL Reaktivität: Human IHC, WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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anti-Premelanosome Protein (PMEL) (C-Term) antibodyPMEL Reaktivität: Human, Maus IF, IHC, WB, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Premelanosome Protein (PMEL) antibodyPMEL Reaktivität: Human, Ratte, Maus IHC, WB Wirt: Kaninchen Polyclonal unconjugated
anti-Premelanosome Protein (PMEL) antibodyPMEL Reaktivität: Human IHC Wirt: Kaninchen Monoclonal MSVA-617R unconjugated Recombinant Antibody
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Andere Bezeichnung
- PMEL (PMEL Produkte)
- Hintergrund
- This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.,PMEL,D12S53E,ME20,ME20-M,ME20M,P1,P100,PMEL17,SI,SIL,SILV,gp100,Cancer,Tumor immunology,Tumor-associated antigens,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Immunology & Inflammation,PMEL
- Molekulargewicht
- 60kDa/66kDa/70kDa
- Gen-ID
- 6490
- UniProt
- P40967
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