PPM1F Antikörper (AA 1-190)

Produktnummer ABIN7269682

Produktdetails anti-PPM1F Antikörper

Target: PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))

Bindungsspezifität: AA 1-190

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPM1F Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: PPM1F Rabbit pAb

Sequenz: MSSGAPQKSS PMASGAEETP GFLDTLLQDF PALLNPEDPL PWKAPGTVLS QEEVEGELAE LAMGFLGSRK APPPLAAALA HEAVSQLLQT DLSEFRKLPR EEEEEEEDDD EEEKAPVTLL DAQSLAQSFF NRLWEVAGQW QKQVPLAARA SQRQWLVSIH AIRNTRRKME DRHVSLPSFN QLFGLSDPVN

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PPM1F (NP_055449.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PPM1F

Target: PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))

Andere Bezeichnung: PPM1F (PPM1F Produkte)

Synonyme: 1110021B16Rik antikoerper, 4933427B07Rik antikoerper, CaMKPase antikoerper, Popx2 antikoerper, mKIAA0015 antikoerper, CAMKP antikoerper, FEM-2 antikoerper, POPX2 antikoerper, hFEM-2 antikoerper, protein phosphatase, Mg2+/Mn2+ dependent 1F antikoerper, protein phosphatase 1F (PP2C domain containing) antikoerper, protein phosphatase, Mg2+/Mn2+ dependent, 1F antikoerper, PPM1F antikoerper, Ppm1f antikoerper

Hintergrund: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.,PPM1F,CAMKP,CaMKPase,FEM-2,POPX2,hFEM-2,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Calcium Signaling,PPM1F

Molekulargewicht: 38kDa/49kDa

Gen-ID: 9647

UniProt: P49593

Pathways: Positive Regulation of Endopeptidase Activity