PZ antikoerper, 1300015B06Rik antikoerper, betaH1 antikoerper, protein Z, vitamin K dependent plasma glycoprotein antikoerper, protein Z, vitamin K-dependent plasma glycoprotein antikoerper, protein Z, vitamin K-dependent plasma glycoprotein b antikoerper, hemoglobin Z, beta-like embryonic chain antikoerper, PROZ antikoerper, Proz antikoerper, prozb antikoerper, Hbb-bh1 antikoerper
Hintergrund
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.,PROZ,PZ,Cell Biology & Developmental Biology,Ubiquitin,Cardiovascular,Blood,Coagulation,Serum Proteins,PROZ