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PDP Antikörper (AA 72-260)

PDP Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7269774
  • Target Alle PDP Antikörper anzeigen
    PDP (Pyruvate Dehydrogenase Phosphatase (PDP))
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 72-260
    Reaktivität
    • 52
    • 13
    • 11
    • 1
    Human
    Wirt
    • 50
    • 1
    • 1
    Kaninchen
    Klonalität
    • 51
    • 1
    Polyklonal
    Konjugat
    • 17
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PDP Antikörper ist unkonjugiert
    Applikation
    • 38
    • 21
    • 18
    • 13
    • 13
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Verwendungszweck
    PDP1 Rabbit pAb
    Sequenz
    ASTPQKFYLT PPQVNSILKA NEYSFKVPEF DGKNVSSILG FDSNQLPANA PIEDRRSAAT CLQTRGMLLG VFDGHAGCAC SQAVSERLFY YIAVSLLPHE TLLEIENAVE SGRALLPILQ WHKHPNDYFS KEASKLYFNS LRTYWQELID LNTGESTDID VKEALINAFK RLDNDISLEA QVGDPNSFL
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 72-260 of human PDP1 (NP_060914.2).
    Isotyp
    IgG
    Top Product
    Discover our top product PDP Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PDP (Pyruvate Dehydrogenase Phosphatase (PDP))
    Andere Bezeichnung
    PDP1 (PDP Produkte)
    Synonyme
    153332_at antikoerper, CG12151 antikoerper, Dmel\\CG12151 antikoerper, PDP antikoerper, pdp antikoerper, PDH antikoerper, PDPC antikoerper, PPM2C antikoerper, Gm1024 antikoerper, Ppm2c antikoerper, im:7157162 antikoerper, zgc:174908 antikoerper, pdp1 antikoerper, ppm2c antikoerper, Pyruvate dehydrogenase phosphatase antikoerper, pyruvate dehydrogenase [acetyl-transferring]-phosphatase 1, mitochondrial antikoerper, pyruvate dehyrogenase phosphatase catalytic subunit 1 antikoerper, pyruvate dehyrogenase phosphatase catalytic subunit 1 L homeolog antikoerper, Pdp antikoerper, LOC413080 antikoerper, PDP1 antikoerper, Pdp1 antikoerper, pdp1 antikoerper, pdp1.L antikoerper
    Hintergrund
    Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported, one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.,PDP1,PDH,PDP,PDPC,PPM2A,PPM2C,PDP1
    Molekulargewicht
    61kDa/63kDa
    Gen-ID
    54704
    UniProt
    Q9P0J1
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