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RAD50 Antikörper

RAD50 Reaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
Produktnummer ABIN7269826
  • Target Alle RAD50 Antikörper anzeigen
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    Reaktivität
    • 47
    • 38
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 53
    • 5
    Kaninchen
    Klonalität
    • 52
    • 6
    Monoklonal
    Konjugat
    • 34
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RAD50 Antikörper ist unkonjugiert
    Applikation
    • 54
    • 17
    • 16
    • 16
    • 13
    • 13
    • 10
    • 9
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rad50 Rabbit mAb
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Monoclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthesized peptide derived from human Rad50
    Isotyp
    IgG
    Top Product
    Discover our top product RAD50 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    Andere Bezeichnung
    RAD50 (RAD50 Produkte)
    Hintergrund
    The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010],NBSLD, RAD502, hRad50,Cell Biology & Developmental Biology,Cell Cycle,DNA Damage & Repair,Epigenetics & Nuclear Signaling,G2/M DNA Damage Checkpoint,RAD50
    Molekulargewicht
    154kDa
    Gen-ID
    10111
    UniProt
    Q92878
    Pathways
    DNA Reparatur, Protein targeting to Nucleus
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