RSAD2 Antikörper (AA 42-361)
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- Target Alle RSAD2 Antikörper anzeigen
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
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Bindungsspezifität
- AA 42-361
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RSAD2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Verwendungszweck
- RSAD2 Rabbit pAb
- Sequenz
- LATKRRKQQL VLRGPDETKE EEEDPPLPTT PTSVNYHFTR QCNYKCGFCF HTAKTSFVLP LEEAKRGLLL LKEAGMEKIN FSGGEPFLQD RGEYLGKLVR FCKVELRLPS VSIVSNGSLI RERWFQNYGE YLDILAISCD SFDEEVNVLI GRGQGKKNHV ENLQKLRRWC RDYRVAFKIN SVINRFNVEE DMTEQIKALN PVRWKVFQCL LIEGENCGED ALREAERFVI GDEEFERFLE RHKEVSCLVP ESNQKMKDSY LILDEYMRFL NCRKGRKDPS KSILDVGVEE AIKFSGFDEK MFLKRGGKYI WSKADLKLDW
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 42-361 of human RSAD2 (NP_542388.2).
- Isotyp
- IgG
- Top Product
- Discover our top product RSAD2 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
- Andere Bezeichnung
- RSAD2 (RSAD2 Produkte)
- Hintergrund
- Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Catalyzes the conversion of cytidine triphosphate (CTP to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP via a SAM-dependent radical mechanism. In turn, ddhCTP acts as a chain terminator for the RNA-dependent RNA polymerases from multiple viruses and directly inhibits viral replication. Therefore, inhibits a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV, hepatitis C virus (HCV, west Nile virus (WNV, dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV, zika virus, and human immunodeficiency virus (HIV-1. Promotes also TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs by facilitating 'Lys-63'-linked ubiquitination of IRAK1 by TRAF6. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR-mediated GATA3 activation and optimal T-helper 2 (Th2 cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.,RSAD2,2510004L01Rik,cig33,cig5,vig1,Immunology & Inflammation,RSAD2
- Molekulargewicht
- 42kDa
- Gen-ID
- 91543
- UniProt
- Q8WXG1
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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