RASD1 Antikörper (AA 132-281)

Produktnummer ABIN7269879

Produktdetails anti-RASD1 Antikörper

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Bindungsspezifität: AA 132-281

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: RASD1 Rabbit pAb

Sequenz: TKENVDVPLV ICGNKGDRDF YREVDQREIE QLVGDDPQRC AYFEISAKKN SSLDQMFRAL FAMAKLPSEM SPDLHRKVSV QYCDVLHKKA LRNKKLLRAG SGGGGGDPGD AFGIVAPFAR RPSVHSDLMY IREKASAGSQ AKDKERCVIS

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 132-281 of human RASD1 (NP_057168.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RASD1

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Andere Bezeichnung: RASD1 (RASD1 Produkte)

Hintergrund: This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RASD1,AGS1,DEXRAS1,MGC:26290,Signal Transduction,G protein signaling,Signal Transduction,RASD1

Molekulargewicht: 13kDa/31kDa

Gen-ID: 51655

UniProt: Q9Y272