RGS4 Antikörper (AA 1-100)

Produktnummer ABIN7269898

Produktdetails anti-RGS4 Antikörper

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: RGS4 Rabbit pAb

Sequenz: MCKGLAGLPA SCLRSAKDMK HRLGFLLQKS DSCEHNSSHN KKDKVVICQR VSQEEVKKWA ESLENLISHE CGLAAFKAFL KSEYSEENID FWISCEEYKK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RGS4 (NP_005604.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RGS4

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Andere Bezeichnung: RGS4 (RGS4 Produkte)

Synonyme: RGP4 antikoerper, SCZD9 antikoerper, AA004315 antikoerper, AA597169 antikoerper, ESTM48 antikoerper, ESTM50 antikoerper, regulator of G protein signaling 4 antikoerper, regulator of G-protein signaling 4 antikoerper, RGS4 antikoerper, Rgs4 antikoerper

Hintergrund: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.,RGS4,RGP4,SCZD9,Signal Transduction,G protein signaling,Signal Transduction,G2/M DNA Damage Checkpoint,Cardiovascular,Heart,Cardiac arrhythmias,Hypertrophy,RGS4

Molekulargewicht: 10kDa/21kDa/23kDa/33kDa

Gen-ID: 5999

UniProt: P49798

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling