Reticulon 3 Antikörper (C-Term)

Produktnummer ABIN7269929

Produktdetails anti-Reticulon 3 Antikörper

Target: Reticulon 3 (RTN3)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Reticulon 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: RTN3 Rabbit pAb

Sequenz: YKSVIQAVQK SEEGHPFKAY LDVDITLSSE AFHNYMNAAM VHINRALKLI IRLFLVEDLV DSLKLAVFMW LMTYVGAVFN GITLLILAEL LIFSVPIVYE KYKTQIDHYV GIARDQTKSI VEKIQAKLPG IAKKKAE

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RTN3 (NP_006045.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Reticulon 3

Target: Reticulon 3 (RTN3)

Andere Bezeichnung: RTN3 (RTN3 Produkte)

Hintergrund: This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.,RTN3,ASYIP,HAP,NSPL2,NSPLII,RTN3-A1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,RTN3

Molekulargewicht: 23kDa/25kDa/26kDa/27kDa/100kDa/110kDa/112kDa

Gen-ID: 10313

UniProt: O95197