Retinoblastoma 1 Antikörper (pSer780)
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- Target Alle Retinoblastoma 1 (RB1) Antikörper anzeigen
- Retinoblastoma 1 (RB1)
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Bindungsspezifität
- pSer780
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser Retinoblastoma 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Verwendungszweck
- Phospho-RB-S780 Rabbit mAb
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Phosphorylated Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A phospho synthetic peptide corresponding to residues surrounding S780 of human RB.
- Isotyp
- IgG
- Top Product
- Discover our top product RB1 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Retinoblastoma 1 (RB1)
- Andere Bezeichnung
- RB1 (RB1 Produkte)
- Hintergrund
- The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],OSRC,PPP1R130,RB,p105-Rb,pRb,pp110,RB1,Rb,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,DNA Damage & Repair,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Protein phosphorylation,Transcription Factors,Tumor suppressors,RB1
- Molekulargewicht
- 106kDa
- Gen-ID
- 5925
- UniProt
- P06400
- Pathways
- Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagie
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