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Retinoblastoma 1 Antikörper (pSer780)

RB1 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
Produktnummer ABIN7269936
  • Target Alle Retinoblastoma 1 (RB1) Antikörper anzeigen
    Retinoblastoma 1 (RB1)
    Bindungsspezifität
    • 34
    • 26
    • 25
    • 23
    • 21
    • 21
    • 18
    • 15
    • 11
    • 11
    • 10
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer780
    Reaktivität
    • 289
    • 120
    • 105
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 252
    • 39
    Kaninchen
    Klonalität
    • 248
    • 43
    Monoklonal
    Konjugat
    • 133
    • 17
    • 16
    • 16
    • 11
    • 10
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Retinoblastoma 1 Antikörper ist unkonjugiert
    Applikation
    • 209
    • 119
    • 106
    • 80
    • 79
    • 38
    • 31
    • 28
    • 28
    • 21
    • 17
    • 8
    • 8
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Phospho-RB-S780 Rabbit mAb
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Phosphorylated Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A phospho synthetic peptide corresponding to residues surrounding S780 of human RB.
    Isotyp
    IgG
    Top Product
    Discover our top product RB1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Retinoblastoma 1 (RB1)
    Andere Bezeichnung
    RB1 (RB1 Produkte)
    Synonyme
    OSRC antikoerper, RB antikoerper, p105-Rb antikoerper, pRb antikoerper, pp110 antikoerper, Rb antikoerper, Rb-1 antikoerper, P105-RB antikoerper, PP110 antikoerper, RB11 antikoerper, zgc:154147 antikoerper, RB transcriptional corepressor 1 antikoerper, RB transcriptional corepressor like 1 antikoerper, retinoblastoma 1 antikoerper, RB1 antikoerper, RBL1 antikoerper, Rb1 antikoerper, rb1 antikoerper
    Hintergrund
    The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],OSRC,PPP1R130,RB,p105-Rb,pRb,pp110,RB1,Rb,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,DNA Damage & Repair,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Protein phosphorylation,Transcription Factors,Tumor suppressors,RB1
    Molekulargewicht
    106kDa
    Gen-ID
    5925
    UniProt
    P06400
    Pathways
    Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagie
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