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p107 Antikörper (AA 100-200)

RBL1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7269942
  • Target Alle p107 (RBL1) Antikörper anzeigen
    p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
    Bindungsspezifität
    • 18
    • 15
    • 8
    • 8
    • 8
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-200
    Reaktivität
    • 78
    • 19
    • 10
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 74
    • 4
    Kaninchen
    Klonalität
    • 75
    • 3
    Polyklonal
    Konjugat
    • 31
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser p107 Antikörper ist unkonjugiert
    Applikation
    • 65
    • 38
    • 27
    • 27
    • 11
    • 9
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    RBL1 Rabbit pAb
    Kreuzreaktivität
    Human
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RBL1 (NP_002886.2).
    Isotyp
    IgG
    Top Product
    Discover our top product RBL1 Primärantikörper
  • Applikationshinweise
    WB,1:1000 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
    Andere Bezeichnung
    RBL1 (RBL1 Produkte)
    Synonyme
    p107 antikoerper, prb1 antikoerper, fj58e06 antikoerper, wu:fj58e06 antikoerper, CP107 antikoerper, PRB1 antikoerper, AW547426 antikoerper, retinoblastoma-like 1 L homeolog antikoerper, RB transcriptional corepressor like 1 antikoerper, retinoblastoma-like 1 (p107) antikoerper, retinoblastoma-like 1 antikoerper, rbl1.L antikoerper, RBL1 antikoerper, rbl1 antikoerper, Rbl1 antikoerper
    Hintergrund
    The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.,PRB1, p107, CP107,RBL1
    Molekulargewicht
    120kDa
    Gen-ID
    5933
    UniProt
    P28749
    Pathways
    Zellzyklus, Mitotic G1-G1/S Phases
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