p130 Antikörper (AA 100-200)
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- Target Alle p130 (RBL2) Antikörper anzeigen
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
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Bindungsspezifität
- AA 100-200
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser p130 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Verwendungszweck
- RBL2 Rabbit pAb
- Sequenz
- PTVSKGTVEG NYVSLTRILK CSEQSLIEFF NKMKKWEDMA NLPPHFRERT ERLERNFTVS AVIFKKYEPI FQDIFKYPQE EQPRQQRGRK QRRQPCTVSE I
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RBL2 (NP_005602.3).
- Isotyp
- IgG
- Top Product
- Discover our top product RBL2 Primärantikörper
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anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 165-194), (N-Term) antibody
RBL2 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB31021 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 939-1139) antibodyRBL2 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 2C8A8 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 26-367) antibodyRBL2 Reaktivität: Human, Ratte, Maus, Blow Fly, Huhn WB, IF, IHC, IP Wirt: Maus Monoclonal 10-Rb2 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reaktivität: Ratte, Maus IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 878-913) antibodyRBL2 Reaktivität: Human, Ratte WB, IF, IHC, IHC (p), IP Wirt: Maus Monoclonal 130P215 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 417-616) antibodyRBL2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reaktivität: Human, Ratte, Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reaktivität: Human, Ratte, Maus ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 416-515) antibodyRBL2 Reaktivität: Human ELISA, WB Wirt: Maus Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reaktivität: Human, Schimpanse ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
- Andere Bezeichnung
- RBL2 (RBL2 Produkte)
- Synonyme
- RBL2 antikoerper, RBR2 antikoerper, RRB2a antikoerper, PRB2 antikoerper, RBR-2 antikoerper, Rb2 antikoerper, p130 antikoerper, P130 antikoerper, retinoblastoma-like 2 (p130) antikoerper, RB transcriptional corepressor like 2 antikoerper, related to retinoblastoma 2 antikoerper, RBL2 antikoerper, LOC541652 antikoerper, Rbl2 antikoerper
- Hintergrund
- Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.,RBL2,P130,Rb2,Epigenetics & Nuclear Signaling,Transcription Factors,RBL2
- Molekulargewicht
- 59kDa/128kDa
- Gen-ID
- 5934
- UniProt
- Q08999
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
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