SPARC Antikörper (AA 18-303)

Produktnummer ABIN7270183

Produktdetails anti-SPARC Antikörper

Target: SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))

Bindungsspezifität: AA 18-303

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPARC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: SPARC Rabbit pAb

Sequenz: APQQEALPDE TEVVEETVAE VTEVSVGANP VQVEVGEFDD GAEETEEEVV AENPCQNHHC KHGKVCELDE NNTPMCVCQD PTSCPAPIGE FEKVCSNDNK TFDSSCHFFA TKCTLEGTKK GHKLHLDYIG PCKYIPPCLD SELTEFPLRM RDWLKNVLVT LYERDEDNNL LTEKQKLRVK KIHENEKRLE AGDHPVELLA RDFEKNYNMY IFPVHWQFGQ LDQHPIDGYL SHTELAPLRA PLIPMEHCTT RFFETCDLDN DKYIALDEWA GCFGIKQKDI DKDLVI

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-303 of human SPARC (NP_003109.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SPARC

Target: SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))

Andere Bezeichnung: SPARC (SPARC Produkte)

Synonyme: ON antikoerper, AA517111 antikoerper, BM-40 antikoerper, hm:zeh0062 antikoerper, SPARC antikoerper, sparc antikoerper, secreted protein acidic and cysteine rich antikoerper, secreted acidic cysteine rich glycoprotein antikoerper, secreted protein, acidic, cysteine-rich (osteonectin) antikoerper, secreted protein, acidic, cysteine-rich (osteonectin) L homeolog antikoerper, secreted protein, acidic, cysteine-rich (osteonectin) S homeolog antikoerper, SPARC antikoerper, Sparc antikoerper, sparc antikoerper, sparc.L antikoerper, sparc.S antikoerper

Hintergrund: This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.,SPARC,BM-40,OI17,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cytoskeleton,Extracellular Matrix,Bone,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Angiogenesis,SPARC

Molekulargewicht: 34kDa

Gen-ID: 6678

UniProt: P09486

Pathways: Autophagie