SESN1 Antikörper
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- Target Alle SESN1 Antikörper anzeigen
- SESN1 (Sestrin 1 (SESN1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser SESN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Verwendungszweck
- sestrin 1 Rabbit mAb
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Monoclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthesized peptide derived from human sestrin 1
- Isotyp
- IgG
- Top Product
- Discover our top product SESN1 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SESN1 (Sestrin 1 (SESN1))
- Andere Bezeichnung
- SESN1 (SESN1 Produkte)
- Synonyme
- zgc:91970 antikoerper, sestrin-1 antikoerper, SESN1 antikoerper, XPA26 antikoerper, pa26 antikoerper, sest1 antikoerper, PA26 antikoerper, SEST1 antikoerper, 1110002G11Rik antikoerper, AU044290 antikoerper, Pa26 antikoerper, Sest1 antikoerper, sesn1-A antikoerper, sestrin 1 antikoerper, sestrin 1 L homeolog antikoerper, SESN1 antikoerper, sesn1 antikoerper, Sesn1 antikoerper, sesn1.L antikoerper
- Hintergrund
- This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],PA26, SEST1,AMPK Signaling Pathway,Cell Biology & Developmental Biology,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Obesity,SESN1
- Molekulargewicht
- 70kDa
- Gen-ID
- 27244
- UniProt
- Q9Y6P5
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