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SETD4 Antikörper (AA 210-300)

SETD4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7270264
  • Target Alle SETD4 Produkte
    SETD4 (SET Domain Containing 4 (SETD4))
    Bindungsspezifität
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 210-300
    Reaktivität
    • 17
    • 14
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 16
    • 1
    Kaninchen
    Klonalität
    • 17
    Polyklonal
    Konjugat
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SETD4 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 9
    Western Blotting (WB)
    Verwendungszweck
    SETD4 Rabbit pAb
    Sequenz
    YLRPRQRECL SAEPDTCALA PYLDLLNHSP HVQVKAAFNE ETHSYEIRTT SRWRKHEEVF ICYGPHDNQR LFLEYGFVSV HNPHACVYVS R
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 210-300 of human SETD4 (NP_001007260).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SETD4 (SET Domain Containing 4 (SETD4))
    Andere Bezeichnung
    SETD4 (SETD4 Produkte)
    Hintergrund
    Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response. Regulates the inflammatory response by mediating mono- and dimethylation of 'Lys-4' of histone H3 (H3K4me1 and H3K4me2, respectively, leading to activate the transcription of proinflammatory cytokines IL6 and TNF-alpha (By similarity. Also involved in the regulation of stem cell quiescence by catalyzing the trimethylation of 'Lys-20' of histone H4 (H4K20me3, thereby promoting heterochromatin formation. Involved in proliferation, migration, paracrine and myogenic differentiation of bone marrow mesenchymal stem cells (BMSCs (By similarity.,C21orf18,C21orf27,SETD4,Epigenetics & Nuclear Signaling,SETD4
    Gen-ID
    54093
    UniProt
    Q9NVD3
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