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SGPL1 Antikörper (AA 60-390)

SGPL1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7270533
  • Target Alle SGPL1 Antikörper anzeigen
    SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 60-390
    Reaktivität
    • 32
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 32
    • 2
    Kaninchen
    Klonalität
    • 35
    Polyklonal
    Konjugat
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SGPL1 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 17
    • 16
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    SGPL1 Rabbit pAb
    Sequenz
    VFQPESLWSR FKKKCFKLTR KMPIIGRKIQ DKLNKTKDDI SKNMSFLKVD KEYVKALPSQ GLSSSAVLEK LKEYSSMDAF WQEGRASGTV YSGEEKLTEL LVKAYGDFAW SNPLHPDIFP GLRKIEAEIV RIACSLFNGG PDSCGCVTSG GTESILMACK AYRDLAFEKG IKTPEIVAPQ SAHAAFNKAA SYFGMKIVRV PLTKMMEVDV RAMRRAISRN TAMLVCSTPQ FPHGVIDPVP EVAKLAVKYK IPLHVDACLG GFLIVFMEKA GYPLEHPFDF RVKGVTSISA DTHKYGYAPK GSSLVLYSDK KYRNYQFFVD TDWQGGIYAS P
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 60-390 of human SGPL1 (NP_003892.2).
    Isotyp
    IgG
    Top Product
    Discover our top product SGPL1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))
    Andere Bezeichnung
    SGPL1 (SGPL1 Produkte)
    Synonyme
    SGPL1 antikoerper, zgc:162153 antikoerper, AI428538 antikoerper, D10Xrf456 antikoerper, S1PL antikoerper, Spl antikoerper, SPL antikoerper, Spgl1 antikoerper, spl antikoerper, sphingosine-1-phosphate lyase 1 antikoerper, sphingosine-1-phosphate lyase 1 L homeolog antikoerper, sphingosine phosphate lyase 1 antikoerper, SGPL1 antikoerper, sgpl1.L antikoerper, sgpl1 antikoerper, Sgpl1 antikoerper
    Hintergrund
    Cleaves phosphorylated sphingoid bases (PSBs, such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts. Involved in the regulation of pro-inflammatory response and neutrophil trafficking. Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP (By similarity. Seems to play a role in establishing neuronal contact sites and axonal maintenance (By similarity.,SGPL1,S1PL,SPL,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,SGPL1
    Molekulargewicht
    63kDa
    Gen-ID
    8879
    UniProt
    O95470
    Pathways
    Platelet-derived growth Factor Receptor Signaling
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