SF3B1 Antikörper
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- Target Alle SF3B1 Antikörper anzeigen
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser SF3B1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Verwendungszweck
- SF3B1 Rabbit mAb
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Monoclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthesized peptide derived from human SF3B1
- Isotyp
- IgG
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
- Andere Bezeichnung
- SF3B1 (SF3B1 Produkte)
- Hintergrund
- This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155,Epigenetics & Nuclear Signaling,Protein phosphorylation,RNA Binding,SF3B1
- Molekulargewicht
- 155kDa
- Gen-ID
- 23451
- UniProt
- O75533
- Pathways
- Chromatin Binding
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