Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TNKS Antikörper (AA 1050-1150)

TNKS Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7270725
  • Target Alle TNKS Antikörper anzeigen
    TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))
    Bindungsspezifität
    • 10
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1050-1150
    Reaktivität
    • 37
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 32
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 34
    • 3
    Polyklonal
    Konjugat
    • 25
    • 4
    • 2
    • 2
    • 2
    • 2
    Dieser TNKS Antikörper ist unkonjugiert
    Applikation
    • 31
    • 21
    • 18
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    TNKS Rabbit pAb
    Sequenz
    EQITLDVLAD MGHEELKEIG INAYGHRHKL IKGVERLLGG QQGTNPYLTF HCVNQGTILL DLAPEDKEYQ SVEEEMQSTI REHRDGGNAG GIFNRYNVIR I
    Kreuzreaktivität
    Human
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 1050-1150 of human TNKS (NP_003738.2).
    Isotyp
    IgG
    Top Product
    Discover our top product TNKS Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))
    Andere Bezeichnung
    TNKS (TNKS Produkte)
    Synonyme
    wu:fe02c12 antikoerper, ARTD5 antikoerper, PARP-5a antikoerper, PARP5A antikoerper, PARPL antikoerper, TIN1 antikoerper, TINF1 antikoerper, TNKS1 antikoerper, pART5 antikoerper, 4930554K12Rik antikoerper, AI662855 antikoerper, C86528 antikoerper, D130072O21Rik antikoerper, TANK1 antikoerper, mTNKS1 antikoerper, tankyrase-1 antikoerper, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b antikoerper, tankyrase antikoerper, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase antikoerper, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 S homeolog antikoerper, tnksb antikoerper, TNKS antikoerper, Tnks antikoerper, tnks2.S antikoerper
    Hintergrund
    Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length. Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. May be involved in spindle pole assembly through PARsylation of NUMA1. Stimulates 26S proteasome activity.,TNKS,ARTD5,PARP-5a,PARP5A,PARPL,TIN1,TINF1,TNKS1,pART5,tankyrase,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Wnt/β-Catenin Signaling Pathway,TNKS
    Molekulargewicht
    67kDa/142kDa
    Gen-ID
    8658
    UniProt
    O95271
Sie sind hier:
Kundenservice