TPMT Antikörper

Produktnummer ABIN7270797

Produktdetails anti-TPMT Antikörper

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TPMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: TPMT Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of Human TPMT.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TPMT

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Andere Bezeichnung: TPMT (TPMT Produkte)

Synonyme: MGC84277 antikoerper, AW106912 antikoerper, NHLRC1 antikoerper, thiopurine S-methyltransferase L homeolog antikoerper, thiopurine S-methyltransferase, tandem duplicate 2 antikoerper, thiopurine S-methyltransferase TpmT antikoerper, thiopurine S-methyltransferase antikoerper, Thiopurine S-methyltransferase antikoerper, thiopurine methyltransferase antikoerper, tpmt.L antikoerper, tpmt.2 antikoerper, tpmT antikoerper, MCA0794 antikoerper, Pnap_4948 antikoerper, Hhal_1383 antikoerper, TK90_1044 antikoerper, Slit_1144 antikoerper, Tint_0842 antikoerper, Fbal_3334 antikoerper, Celly_3188 antikoerper, Weevi_1737 antikoerper, Psefu_2696 antikoerper, Metme_3860 antikoerper, Tpmt antikoerper, TPMT antikoerper

Hintergrund: This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.,TPMT,TPMTD,Signal Transduction,Endocrine & Metabolism,Drug metabolism,TPMT

Molekulargewicht: 28kDa

Gen-ID: 7172

UniProt: P51580