TOP1MT Antikörper (AA 470-550)

Produktnummer ABIN7270851

Produktdetails anti-TOP1MT Antikörper

Target: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Bindungsspezifität: AA 470-550

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOP1MT Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Verwendungszweck: TOP1MT Rabbit pAb

Sequenz: RATPSTFEKS MQNLQTKIQA KKEQVAEARA ELRRARAEHK AQGDGKSRSV LEKKRRLLEK LQEQLAQLSV QATDKEENKQ V

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 470-550 of human TOP1MT (NP_443195.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TOP1MT

Target: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Andere Bezeichnung: TOP1MT (TOP1MT Produkte)

Hintergrund: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,TOP1MT,Epigenetics & Nuclear Signaling,Cancer,Drug resistance,Topoisomerases,TOP1MT

Molekulargewicht: 58kDa/69kDa

Gen-ID: 116447

UniProt: Q969P6