TLE1 Antikörper

Produktnummer ABIN7270903

Produktdetails anti-TLE1 Antikörper

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TLE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: TLE1 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human TLE1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000, IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TLE1

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Andere Bezeichnung: TLE1 (TLE1 Produkte)

Synonyme: ESG antikoerper, ESG1 antikoerper, GRG1 antikoerper, C230057C06Rik antikoerper, Estm14 antikoerper, Grg1 antikoerper, Tle4l antikoerper, TLE1 antikoerper, transducin like enhancer of split 1 antikoerper, transducin-like enhancer protein 1 antikoerper, transducin-like enhancer of split 1 antikoerper, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) antikoerper, TLE1 antikoerper, Smp_150080 antikoerper, Tle1 antikoerper, LOC100354911 antikoerper, LOC100524475 antikoerper, LOC100061341 antikoerper

Hintergrund: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.,ESG, ESG1, GRG1,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Stem Cells,Wnt/β-Catenin Signaling Pathway,TLE1

Molekulargewicht: 83kDa

Gen-ID: 7088

UniProt: Q04724

Pathways: WNT Signalweg, SARS-CoV-2 Protein Interaktom