fi42c05 antikoerper, im:7140344 antikoerper, wu:fi42c05 antikoerper, zgc:152898 antikoerper, MGC115225 antikoerper, SHEP10 antikoerper, TPC2 antikoerper, BC025890 antikoerper, D830047E22Rik antikoerper, two pore segment channel 2 antikoerper, two pore segment channel 2 L homeolog antikoerper, two pore calcium channel protein 2 antikoerper, tpcn2 antikoerper, Tpcn2 antikoerper, TPCN2 antikoerper, tpcn2.L antikoerper, LOC100444397 antikoerper
Hintergrund
This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.,TPCN2,SHEP10,TPC2,Signal Transduction,Neuroscience,Calcium Signaling,TPCN2