USP37 Antikörper (AA 150-250)

Produktnummer ABIN7271158

Produktdetails anti-USP37 Antikörper

Target: USP37 (Ubiquitin Specific Peptidase 37 (USP37))

Bindungsspezifität: AA 150-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP37 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: USP37 Rabbit pAb

Sequenz: SLETKDDIPF RKVLGNPGRG SIKTVAGSGI ARTIPSLTST STPLRSGLLE NRTEKRKRMI STGSELNEDY PKENDSSSNN KAMTDPSRKY LTSSREKQLS L

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human USP37 (NP_065986.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu USP37

Target: USP37 (Ubiquitin Specific Peptidase 37 (USP37))

Andere Bezeichnung: USP37 (USP37 Produkte)

Synonyme: 4932415L06Rik antikoerper, C330008N13Rik antikoerper, wu:fi15b04 antikoerper, wu:fi38d03 antikoerper, zgc:152882 antikoerper, zgc:153999 antikoerper, ubiquitin specific peptidase 37 antikoerper, USP37 antikoerper, usp37 antikoerper, Usp37 antikoerper

Hintergrund: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2, thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2. Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1.,USP37,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,USP37

Molekulargewicht: 99kDa/110kDa

Gen-ID: 57695

UniProt: Q86T82