UGT1A10 Antikörper (AA 50-150)

Produktnummer ABIN7271191

Produktdetails anti-UGT1A10 Antikörper

Target: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Bindungsspezifität: AA 50-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGT1A10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: UGT1A10 Rabbit pAb

Sequenz: LRGHEVVVVM PEVSWQLERS LNCTVKTYST SYTLEDQNRE FMVFAHAQWK AQAQSIFSLL MSSSSGFLDL FFSHCRSLFN DRKLVEYLKE SSFDAVFLDP F

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human UGT1A10 (NP_061948.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu UGT1A10

Target: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Andere Bezeichnung: UGT1A10 (UGT1A10 Produkte)

Hintergrund: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.,UGT1A10;UDPGT;UGT-1J;UGT1-10;UGT1.10;UGT1J,Signal Transduction,Endocrine & Metabolism,Drug metabolism,UGT1A10

Molekulargewicht: 49kDa/59kDa

Gen-ID: 54575

UniProt: Q9HAW8

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha