VCPIP1 antikoerper, vcip135 antikoerper, DUBA3 antikoerper, VCIP135 antikoerper, 4932442A08 antikoerper, 5730421J18Rik antikoerper, 5730538E15Rik antikoerper, mKIAA1850 antikoerper, Vcip135 antikoerper, valosin containing protein interacting protein 1 antikoerper, valosin containing protein (p97)/p47 complex interacting protein 1 antikoerper, VCPIP1 antikoerper, vcpip1 antikoerper, Vcpip1 antikoerper
Hintergrund
Deubiquitinating enzyme involved in DNA repair and reassembly of the Golgi apparatus and the endoplasmic reticulum following mitosis. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis (By similarity. Plays a role in VCP-mediated formation of transitional endoplasmic reticulum (tER (By similarity. Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (By similarity. Also involved in DNA repair following phosphorylation by ATM or ATR: acts by catalyzing deubiquitination of SPRTN, thereby promoting SPRTN recruitment to chromatin and subsequent proteolytic cleavage of covalent DNA-protein cross-links (DPCs. Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.,VCPIP1,DUBA3,VCIP135,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,VCPIP1