WASF1 Antikörper (C-Term)

Produktnummer ABIN7271345

Produktdetails anti-WASF1 Antikörper

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WASF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: WASF1 Rabbit pAb

Sequenz: VARAAPVCET VPVHPLPQGE VQGLPPPPPP PPLPPPGIRP SSPVTVTALA HPPSGLHPTP STAPGPHVPL MPPSPPSQVI PASEPKRHPS TLPVISDARS VLLEAIRKGI QLRKVEEQRE QEAKHERIEN DVATILSRRI AVEYSDSEDD SEFDEVDWLE

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human WASF1 (NP_001020107.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu WASF1

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Andere Bezeichnung: WASF1 (WASF1 Produkte)

Hintergrund: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.,WASF1,SCAR1,WAVE,WAVE1,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Extracellular Matrix,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,WASF1

Molekulargewicht: 61kDa

Gen-ID: 8936

UniProt: Q92558

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization