WASP Antikörper

Produktnummer ABIN7271381

Produktdetails anti-WASP Antikörper

Target: WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser WASP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: WASP Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human WASP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu WASP

Target: WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

Andere Bezeichnung: WAS (WAS Produkte)

Synonyme: IMD2 antikoerper, SCNX antikoerper, THC antikoerper, THC1 antikoerper, WASP antikoerper, U42471 antikoerper, WASp antikoerper, Wasp antikoerper, imd2 antikoerper, thc antikoerper, thc1 antikoerper, was antikoerper, wasp antikoerper, wu:fk81c08 antikoerper, zgc:64164 antikoerper, Wiskott-Aldrich syndrome antikoerper, neural Wiskott-Aldrich syndrome protein antikoerper, wiskott-aldrich syndrome protein antikoerper, Wiskott-Aldrich syndrome L homeolog antikoerper, Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b antikoerper, WAS antikoerper, LOC5578888 antikoerper, CpipJ_CPIJ006699 antikoerper, Was antikoerper, was.L antikoerper, wasb antikoerper

Hintergrund: The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known. [provided by RefSeq, Jul 2008],IMD2, SCNX, THC, THC1, WASP, WASPA,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,Immunology & Inflammation,Signal Transduction,T Cell Receptor Signaling Pathway,WAS

Molekulargewicht: 60kDa

Gen-ID: 7454

UniProt: P42768