zc3h9 antikoerper, gpatc6 antikoerper, gpatch6 antikoerper, zc3hdc9 antikoerper, GPATC6 antikoerper, GPATCH6 antikoerper, KIAA1847 antikoerper, ZC3H9 antikoerper, ZC3HDC9 antikoerper, ZIP antikoerper, 1500006I01Rik antikoerper, BC021513 antikoerper, RGD1310801 antikoerper, zgc:63730 antikoerper, zinc finger CCCH-type and G-patch domain containing antikoerper, zinc finger, CCCH-type with G-patch domain L homeolog antikoerper, zinc finger, CCCH-type with G-patch domain antikoerper, zinc finger, CCCH-type with G patch domain antikoerper, ZGPAT antikoerper, zgpat.L antikoerper, zgpat antikoerper, Zgpat antikoerper
Hintergrund
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.,ZGPAT,GPATC6,GPATCH6,KIAA1847,ZC3H9,ZC3HDC9,ZIP,Epigenetics & Nuclear Signaling,Transcription Factors,ZGPAT