wu:fi20f07 antikoerper, wu:fi22c06 antikoerper, LRPAP1 antikoerper, DKFZp459I2430 antikoerper, A2MRAP antikoerper, A2RAP antikoerper, HBP44 antikoerper, MRAP antikoerper, RAP antikoerper, AA617339 antikoerper, AI790446 antikoerper, AU042172 antikoerper, C77774 antikoerper, alpha-2-macroglobulin receptor-associated protein-like antikoerper, low density lipoprotein receptor-related protein associated protein 1 antikoerper, LDL receptor related protein associated protein 1 antikoerper, LDL receptor related protein associated protein 1 L homeolog antikoerper, LOC100231803 antikoerper, lrpap1 antikoerper, LRPAP1 antikoerper, Lrpap1 antikoerper, lrpap1.L antikoerper
Hintergrund
39 kDa receptor-associated protein,A2MRAP,A2RAP,Alpha 2 macroglobulin receptor associated protein,Alpha 2 MRAP,Alpha-2-macroglobulin receptor-associated protein,Alpha-2-MRAP,AMRP,HBP44,Lipoprotein receptor associated protein,Low density lipoprotein receptor related protein associated protein 1,Low density lipoprotein receptor-related protein-associated protein 1,Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein,Low density lipoprotein related protein associated protein 1,low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1),Lrpap1,MGC138272,MRAP,MYP23,RAP,Low density lipoprotein receptor-related protein associated protein 1also known asLRPAP1orRAPis a chaperoneproteinwhich in humans is encoded by the LRPAP1gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.