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RAD50 Antikörper

RAD50 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7384000
  • Target Alle RAD50 Antikörper anzeigen
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    Reaktivität
    • 61
    • 51
    • 17
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 67
    • 5
    Kaninchen
    Klonalität
    • 65
    • 7
    Polyklonal
    Konjugat
    • 35
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RAD50 Antikörper ist unkonjugiert
    Applikation
    • 55
    • 17
    • 16
    • 16
    • 13
    • 13
    • 9
    • 9
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Aufreinigung
    Affinity purification
    Immunogen
    Synthetic peptide of human RAD50
    Isotyp
    IgG
    Top Product
    Discover our top product RAD50 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.4 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    Andere Bezeichnung
    RAD50 (RAD50 Produkte)
    Hintergrund
    DNA repair protein RAD50,hRAD50,hsRAD50,Mrell,NBSLD,Rad 50,RAD50 2,rad50,RAD50 homolog (S cerevisiae),RAD50 homolog,RAD50 PEN,RAD50,S. cerevisiae,homolog of,RAD50,RAD502,Rad50l,Truncated RAD50 protein,The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
    Molekulargewicht
    154 kDa
    NCBI Accession
    NP_005723
    UniProt
    Q92878
    Pathways
    DNA Reparatur, Protein targeting to Nucleus
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