SMG7 Antikörper
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- Target Alle SMG7 Antikörper anzeigen
- SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMG7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human SMG7 (NP_963863.2).
- Isotyp
- IgG
- Top Product
- Discover our top product SMG7 Primärantikörper
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- Applikationshinweise
- WB 1:200-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
- Andere Bezeichnung
- SMG7 (SMG7 Produkte)
- Synonyme
- 9430023P16Rik antikoerper, mKIAA0250 antikoerper, C1orf16 antikoerper, EST1C antikoerper, SGA56M antikoerper, Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) antikoerper, SMG7, nonsense mediated mRNA decay factor antikoerper, Smg7 antikoerper, SMG7 antikoerper
- Hintergrund
- SMG7,C1orf16,EST1C,SGA56M,This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD), a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Molekulargewicht
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Observed_MW: 127 kDa
Calculated_MW: 122 kDa/127 kDa/131 kDa
- Gen-ID
- 9887
- UniProt
- Q92540
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