ZNF451 Antikörper
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- Target Alle ZNF451 Antikörper anzeigen
- ZNF451 (Zinc Finger Protein 451 (ZNF451))
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZNF451 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human ZNF451 (NP_001026794.1).
- Isotyp
- IgG
- Top Product
- Discover our top product ZNF451 Primärantikörper
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- Applikationshinweise
- WB 1:200-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ZNF451 (Zinc Finger Protein 451 (ZNF451))
- Andere Bezeichnung
- ZNF451 (ZNF451 Produkte)
- Synonyme
- COASTER antikoerper, dJ417I1.1 antikoerper, 4930515K21Rik antikoerper, 4933435G09Rik antikoerper, AI596398 antikoerper, Kiaa0576-hp antikoerper, Znf451 antikoerper, mKIAA1702 antikoerper, zinc finger protein 451 antikoerper, ZNF451 antikoerper, Zfp451 antikoerper
- Hintergrund
- ZNF451,COASTER,dJ417I1.1,E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation (By similarity). Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9'. Plays a role in regulating the transcription of AR targets.
- Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 63 kDa/115 kDa/121 kDa
- Gen-ID
- 26036
- UniProt
- Q9Y4E5
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