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ZNF451 Antikörper

ZNF451 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7384122
  • Target Alle ZNF451 Antikörper anzeigen
    ZNF451 (Zinc Finger Protein 451 (ZNF451))
    Reaktivität
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 19
    Kaninchen
    Klonalität
    • 19
    Polyklonal
    Konjugat
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ZNF451 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 12
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human ZNF451 (NP_001026794.1).
    Isotyp
    IgG
    Top Product
    Discover our top product ZNF451 Primärantikörper
  • Applikationshinweise
    WB 1:200-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ZNF451 (Zinc Finger Protein 451 (ZNF451))
    Andere Bezeichnung
    ZNF451 (ZNF451 Produkte)
    Synonyme
    COASTER antikoerper, dJ417I1.1 antikoerper, 4930515K21Rik antikoerper, 4933435G09Rik antikoerper, AI596398 antikoerper, Kiaa0576-hp antikoerper, Znf451 antikoerper, mKIAA1702 antikoerper, zinc finger protein 451 antikoerper, ZNF451 antikoerper, Zfp451 antikoerper
    Hintergrund
    ZNF451,COASTER,dJ417I1.1,E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation (By similarity). Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9'. Plays a role in regulating the transcription of AR targets.
    Molekulargewicht

    Observed_MW: Refer to figures

    Calculated_MW: 63 kDa/115 kDa/121 kDa

    Gen-ID
    26036
    UniProt
    Q9Y4E5
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