DMBT1 Antikörper

Produktnummer ABIN7384267

Produktdetails anti-DMBT1 Antikörper

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMBT1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human Deleted in malignant brain tumors 1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:200-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.71 mg/mL

Buffer: PBS with 0.05 % Proclin300, 50 % glycerol, pH 7.3.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DMBT1

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Andere Bezeichnung: DMBT1 (DMBT1 Produkte)

Synonyme: GP340 antikoerper, muclin antikoerper, CRP antikoerper, CRP-[a] antikoerper, CRP-[b] antikoerper, Crpd antikoerper, DBMT1 antikoerper, gp300 antikoerper, p80 antikoerper, DMBT1 antikoerper, gp340 antikoerper, deleted in malignant brain tumors 1 antikoerper, deleted in malignant brain tumors 1 protein antikoerper, gp340 antikoerper, deleted in malignant brain tumors 1 S homeolog antikoerper, DMBT1 antikoerper, Dmbt1 antikoerper, LOC100064515 antikoerper, dmbt1 antikoerper, ST201phi2-1p340 antikoerper, dmbt1.S antikoerper

Hintergrund: Apactin, CRP, Crpd, DBMT1, Deleted in malignant brain tumors 1 protein, DMBT1, DMBT1 prototype precursor, Ebnerin, FLJ61058, Glycoprotein 300, Glycoprotein 340, GP340, Gp340 variant protein, GP340, Hensin, MGC164738, Muclin, p80, Pancrin, SAG, Salivary agglutinin, Surfactant pulmonary associated D binding protein, Vomeroglandin,Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.

Gen-ID: 1755

UniProt: Q9UGM3

Pathways: Activation of Innate immune Response