GSDMD Antikörper

Produktnummer ABIN7384358

Produktdetails anti-GSDMD Antikörper

Target: GSDMD (Gasdermin D (GSDMD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser GSDMD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity Purified

Klon: R06-5C5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GSDMD

Target: GSDMD (Gasdermin D (GSDMD))

Andere Bezeichnung: GSDMD (GSDMD Produkte)

Hintergrund: DF5L,DFNA5L,FKSG10,GSDMDC1,GSDMD,GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently,GSDMD is identified as a new component of inflammasomes,and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Molekulargewicht:

Observed_MW: 53kDa

Calculated_MW: 53kDa

Gen-ID: 79792

UniProt: P57764

Pathways: Inflammasome