YTHDF1 Antikörper

Produktnummer ABIN7384402

Produktdetails anti-YTHDF1 Antikörper

Target: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Reaktivität: Human, Hamster

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser YTHDF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity Purified

Klon: R05-2E7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu YTHDF1

Target: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Andere Bezeichnung: YTHDF1 (YTHDF1 Produkte)

Hintergrund: C20orf21,DF1,YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21, is a 559 amino acid protein, which localizes in the cytoplasm. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation. YTHDF1 exists two isoform and calculated molecular weight of isoforms are 61 kDa and 21 kDa.

Molekulargewicht:

Observed_MW: 61kDa

Calculated_MW: 61kDa

Gen-ID: 54915

UniProt: P59326