YTHDF1 Antikörper
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- Target Alle YTHDF1 Produkte
- YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))
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Reaktivität
- Human, Hamster
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser YTHDF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity Purified
- Klon
- R05-2E7
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:1000-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 300 μg/mL
- Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))
- Andere Bezeichnung
- YTHDF1 (YTHDF1 Produkte)
- Synonyme
- fb49c02 antikoerper, zgc:55657 antikoerper, wu:fb49c02 antikoerper, wu:fi19h06 antikoerper, wu:fj87f09 antikoerper, wu:fp06c11 antikoerper, MGC75606 antikoerper, MGC68505 antikoerper, 2210410K23Rik antikoerper, 8030473O16 antikoerper, C20orf21 antikoerper, YTH N(6)-methyladenosine RNA binding protein 1 antikoerper, YTH N(6)-methyladenosine RNA binding protein 1 L homeolog antikoerper, YTH N6-methyladenosine RNA binding protein 1 antikoerper, YTH domain family 1 antikoerper, ythdf1 antikoerper, ythdf1.L antikoerper, YTHDF1 antikoerper, Ythdf1 antikoerper
- Hintergrund
- C20orf21,DF1,YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21, is a 559 amino acid protein, which localizes in the cytoplasm. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation. YTHDF1 exists two isoform and calculated molecular weight of isoforms are 61 kDa and 21 kDa.
- Molekulargewicht
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Observed_MW: 61kDa
Calculated_MW: 61kDa
- Gen-ID
- 54915
- UniProt
- P59326
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