MCM2 Antikörper

Produktnummer ABIN7384466

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch MCM2 in WB und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für MCM2 Antikörper (ABIN7384466)

Target: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MCM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: R08-9H4

Produktdetails anti-MCM2 Antikörper

Aufreinigung: Affinity Purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MCM2

Target: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Andere Bezeichnung: MCM2

Hintergrund: BM28,CCNL 1,CCNL1,CDC like 1,cdc19,CDCL 1,CDCL1,Cell devision cycle like 1,Cyclin like 1,D3S3194,DNA replication licensing factor MCM2,KIAA0030,MCM 2,MCM2,MCM2 minichromosome maintenance deficient 2 mitotin,MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae),MCM2 minichromosome maintenance deficient 2,mitotin,MCM2,MGC10606,Minichromosome maintenance complex component 2,Minichromosome maintenance deficient 2 (mitotin),Minichromosome maintenance deficient 2 mitotin,Minichromosome maintenance protein 2,Minichromosome maintenance protein 2 homolog,Mitotin,Nuclear protein BM28,OTTHUMP00000216047,OTTHUMP00000216050,The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with mCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. 

Molekulargewicht:

Observed_MW: 125kDa

Calculated_MW: 102kDa

Gen-ID: 4171

UniProt: P49736

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA