GDF5 Antikörper (AA 201-300)

Produktnummer ABIN718376

Produktdetails anti-GDF5 Antikörper

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Bindungsspezifität: AA 201-300

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDMP1/GDF5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GDF5

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Andere Bezeichnung: CDMP1 (GDF5 Produkte)

Synonyme: CDMP1 antikoerper, gdf antikoerper, gdf-5 antikoerper, GDF5 antikoerper, BDA1C antikoerper, BMP14 antikoerper, LAP4 antikoerper, OS5 antikoerper, SYM1B antikoerper, SYNS2 antikoerper, Cdmp-1 antikoerper, bp antikoerper, brp antikoerper, Cdmp1 antikoerper, growth differentiation factor 5 L homeolog antikoerper, growth differentiation factor 5 antikoerper, gdf5.L antikoerper, GDF5 antikoerper, Gdf5 antikoerper

Hintergrund:

Synonyms: Cartilage derived morphogenetic protein 1, Cartilage-derived morphogenetic protein 1, CDMP-1, CDMP1, GDF-5, Gdf 5, GDF5_HUMAN, Growth dferentiation factor 5, Growth/dferentiation factor 5, LAP4, Radotermin.

Background: Defects in GDF5 are the cause of acromesomelic chondrodysplasia Grebe type (AMDG) . Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs, and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers). AMDG is an autosomal recessive form characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of acromesomelic chondrodysplasia Hunter-Thompson type (AMDH). AMDH is an autosomal recessive form of dwarfism. Patients have limb abnormalities, with the middle and distal segments being most affected and the lower limbs more affected than the upper. AMDH is characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of brachydactyly type C (BDC). BDC is an autosomal dominant disorder characterized by an abnormal shortness of the fingers and toes.

Gen-ID: 8200