Arip4 antikoerper, D130058C05 antikoerper, G630026H09Rik antikoerper, Srisnf2l antikoerper, ARIP4 antikoerper, HSPC325 antikoerper, SRISNF2L antikoerper, RAD54 like 2 (S. cerevisiae) antikoerper, RAD54 like 2 antikoerper, Rad54l2 antikoerper, RAD54L2 antikoerper
Hintergrund
Background: ARIP4 (androgen-interacting protein 4) was identified in a yeast two-hybrid screen using the human androgen receptor (AR) as bait. It was found to be a member of the SNF2 (sucrose nonfermenting 2) protein family and to have ATPase activity. ARIP4 is able to activate AR-dependent transcription. Targeted inactivation of ARIP4 results in embryonic lethality and reduced growth potential of embryonic fibroblast. These findings indicate an important role in development and proliferation.