CDC20 Antikörper (AA 50-100)

Produktnummer ABIN7448465

Produktdetails anti-CDC20 Antikörper

Target: CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))

Bindungsspezifität: AA 50-100

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC20 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Verwendungszweck: Rabbit anti-CDC20 IHC Antibody, Affinity Purified

Homologie: Dog,Horse,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Primates,Naked mole rat,Small-eared galago,Thirteen-lined ground squirrel,Crab-eating macaque,Northern white-cheeked gibbon,Chinese hamster

Aufreinigung: Affinity Purified

Immunogen: Between AA 50 and 100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 500 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CDC20

Target: CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))

Andere Bezeichnung: CDC20 (CDC20 Produkte)

Synonyme: X-FZY antikoerper, ba276h19.3 antikoerper, cdc20a antikoerper, fizzy1 antikoerper, p55cdc antikoerper, CDC20A antikoerper, bA276H19.3 antikoerper, p55CDC antikoerper, 2310042N09Rik antikoerper, C87100 antikoerper, cell division cycle 20 antikoerper, cell division cycle 20 L homeolog antikoerper, cell division cycle 20 homolog (S. cerevisiae) antikoerper, cdc20 antikoerper, CDC20 antikoerper, cdc20.L antikoerper, Cdc20 antikoerper

Hintergrund: Background: CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.

Gen-ID: 991

NCBI Accession: NP_001246

UniProt: Q12834