eml4 antikoerper, MGC89332 antikoerper, EML4 antikoerper, C2orf2 antikoerper, ELP120 antikoerper, EMAP-4 antikoerper, EMAPL4 antikoerper, ROPP120 antikoerper, 4930443C24Rik antikoerper, AI644019 antikoerper, echinoderm microtubule associated protein like 4 antikoerper, echinoderm microtubule associated protein like 4 S homeolog antikoerper, Eml4 antikoerper, EML4 antikoerper, eml4 antikoerper, eml4.S antikoerper
Hintergrund
Background: Echinoderm microtubule associated protein like 4 (EML4) has been identified as part of a gene fusion with the kinase domain of the anaplastic lymphoma receptor tyrosine kinase (ALK) in non-small cell lung cancer. EML4 associates with in vitro polymerized microtubules. In the cell, phosphorylated EML4 associates with the mitotic spindle and is essential for proliferation and microtubule network formation.