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BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 175-225) Antikörper
BABAM1
Reaktivität: Human
IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN7448667
Produktdetails
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Target
Alle BRISC and BRCA1 A Complex Member 1 (BABAM1) Antikörper anzeigen
BRISC and BRCA1 A Complex Member 1 (BABAM1)
Bindungsspezifität
Alle Epitope für BABAM1 Antikörper
AA 175-225
Reaktivität
Alle Reaktivitäten für BABAM1 Antikörper
Human
Wirt
Alle Wirte für BABAM1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für BABAM1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für BABAM1 Antikörper
Unkonjugiert
Applikation
Alle Applikationen für BABAM1 Antikörper
Immunohistochemistry (IHC)
Verwendungszweck
Rabbit anti-MERIT40 IHC Antibody, Affinity Purified
Homologie
Mouse,Rat,Bovine,Dog,Horse,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Small-eared galago,Chinese hamster,Northern white-cheeked gibbon,Crab-eating macaque,Thirteen-lined ground squirrel,Little brown bat
Aufreinigung
Affinity Purified
Immunogen
Between AA 175 and 225
Isotyp
IgG
Top Product
Discover our top product BABAM1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
1:100 - 1:500
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
250 μg/mL
Buffer
Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Haltbarkeit
12 months
Antigendetails
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Target
BRISC and BRCA1 A Complex Member 1 (BABAM1)
Andere Bezeichnung
MERIT40 (BABAM1 Produkte )
Hintergrund
Background: MERIT40 (mediator of RAP80 interactions and targeting subunit of 40 kDa) is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites and leads to targeting of the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. MERIT40 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin [taken from the Universal Protein Resource (UniProt) Q9NWV8].
Gen-ID
29086
NCBI Accession
NP_054892
UniProt
Q9NWV8
Pathways
Positive Regulation of Response to DNA Damage Stimulus
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