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PUS1 Antikörper (AA 377-427)

PUS1 Reaktivität: Human IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7448747
  • Target Alle PUS1 Antikörper anzeigen
    PUS1 (Pseudouridylate Synthase 1 (PUS1))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 377-427
    Reaktivität
    • 31
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 31
    • 3
    Kaninchen
    Klonalität
    • 32
    • 2
    Polyklonal
    Konjugat
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PUS1 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 16
    • 16
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Verwendungszweck
    Rabbit anti-PUS1 IHC Antibody, Affinity Purified
    Homologie
    Orangutan,Gorilla,Chimpanzee,White-tufted-ear marmoset,Northern white-cheeked gibbon
    Aufreinigung
    Affinity Purified
    Immunogen
    Between AA 377 and 427
    Isotyp
    IgG
    Top Product
    Discover our top product PUS1 Primärantikörper
  • Applikationshinweise
    1:100 - 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    PUS1 (Pseudouridylate Synthase 1 (PUS1))
    Andere Bezeichnung
    PUS1 (PUS1 Produkte)
    Synonyme
    PUS1 antikoerper, A730013B20Rik antikoerper, MPUS1 antikoerper, mPus1p antikoerper, MLASA1 antikoerper, pseudouridylate synthase 1 antikoerper, pseudouridylate synthase 1, putative antikoerper, pseudouridine synthase 1 antikoerper, PUS1 antikoerper, PVX_093530 antikoerper, PKH_011400 antikoerper, Pus1 antikoerper
    Hintergrund
    Background: Pus1 (pseudouridylate synthase 1) is an enzyme that converts uridine to pseudouridine in non-coding RNA substrates. Pus1 modifies uridines at specific positions in a subset of tRNAs. Pseudouridylation is known to affect the structure of tRNAs and stabilize base-stacking and base-pairing in the anticodon loop. Pus1 activity is important for proper folding and function of tRNAs. Pus1 has also been shown to pseudouridylate SRA (steroid receptor RNA activator) and function as a coactivator. Defects in pseudouridylation are associated with the human disease, MLASA (myopathy with lactic acidosis and sideroblastic anemia), an autosomal recessive oxidative phosphorylataion disorder specific to skeletal muscle and bone marrow.
    Gen-ID
    80324
    NCBI Accession
    NP_079491
    UniProt
    Q9Y606
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