RBM17 Antikörper (AA 25-75)

Produktnummer ABIN7448811

Produktdetails anti-RBM17 Antikörper

Target: RBM17 (RNA Binding Motif Protein 17 (RBM17))

Bindungsspezifität: AA 25-75

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM17 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Verwendungszweck: Rabbit anti-SPF45 IHC Antibody, Affinity Purified

Homologie: Rat,X. laevis,Bovine,Dog,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Chimpanzee,White-tufted-ear marmoset,Tasmanian devil,African elephant,Crab-eating macaque,Naked mole rat,Small-eared galago,Thirteen-lined ground squirrel,Chinese hamster,Gray short-tailed opossum,Ferret,Little brown bat,Northern white-cheeked gibbon

Aufreinigung: Affinity Purified

Immunogen: Between AA 25 and 75

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu RBM17

Target: RBM17 (RNA Binding Motif Protein 17 (RBM17))

Andere Bezeichnung: SPF45 (RBM17 Produkte)

Hintergrund: Background: Splicing factor 45 (SPF45) is an RNA splicing factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. SPF45 is involved in the regulation of alternative splicing and the utilization of cryptic splice sites. It has been shown to promote the utilization of a cryptic splice site created by the beta-110 mutation in the human beta-thalassemia gene. The resulting frameshift leads to sickle cell anemia [taken from the Universal Protein Resource (UniProt) Q96125].

Gen-ID: 84991

NCBI Accession: NP_116294

UniProt: Q96I25