HSD17B6 Antikörper (AA 61-160) (Biotin)

Produktnummer ABIN718558

Produktdetails anti-HSD17B6 Antikörper (Biotin)

Target: HSD17B6 (Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))

Bindungsspezifität: AA 61-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B6 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSD17B6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu HSD17B6

Target: HSD17B6 (Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))

Andere Bezeichnung: HSD17B6 (HSD17B6 Produkte)

Synonyme: HSE antikoerper, RODH antikoerper, SDR9C6 antikoerper, 17betaHSD9 antikoerper, Hsd17b9 antikoerper, Rdh8 antikoerper, hydroxysteroid 17-beta dehydrogenase 6 antikoerper, hydroxysteroid (17-beta) dehydrogenase 6 antikoerper, HSD17B6 antikoerper, Hsd17b6 antikoerper

Hintergrund:

Synonyms: 17-beta-HSD 6, 17-beta-HSD6, 17-beta-hydroxysteroid dehydrogenase type 6, 3 hydroxysteroid epimerase, 3alpha >beta hydroxysteroid epimerase, 3alpha >beta hydroxysteroid epimerasel, 3-alpha->beta-HSE, 3-alpha->beta-hydroxysteroid epimerase, H17B6_HUMAN, HSD17B6, HSE, Hydroxysteroid 17 beta dehydrogenase 6, Hydroxysteroid 17 beta dehydrogenase 6 homolog mouse, Hydroxysteroid 17 beta dehydrogenase 6, NAD+ dependent 3 alpha hydroxysteroid dehydrogenase 3 hydroxysteroid epimerase, NAD+ dependent 3 alpha hydroxysteroid dehydrogenase, Oxidative 3 alpha hydroxysteroid dehydrogenase, Oxidative 3-alpha hydroxysteroid dehydrogenase, Oxidoreductase, Retinol dehydrogenase, RODH, SDR9C6,Short chain dehydrogenase/reductase family 9C, member 6.

Background: NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.Tissue specificity, Detected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain.Sequence similarities, Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Gen-ID: 8630

Pathways: Steroid Hormone Biosynthesis