NHEJ1 antikoerper, zgc:85657 antikoerper, XLF antikoerper, 1700029B21Rik antikoerper, cernunnos antikoerper, non-homologous end joining factor 1 antikoerper, non-homologous end joining factor 1 S homeolog antikoerper, solute carrier family 23 member 3 antikoerper, nonhomologous end-joining factor 1 antikoerper, NHEJ1 antikoerper, nhej1.S antikoerper, nhej1 antikoerper, SLC23A3 antikoerper, Nhej1 antikoerper
Hintergrund
Background: XRCC4-like factor (XLF) functions in DNA nonhomologous end joining (NHEJ) in double-strand break repair and immune system V(D)J recombination. Mutations of XLF in humans have been documented to result in immunodeficiency, growth retardation, and microcephaly. The yeast of homolog of XLF is Nej1. XLF has been shown to interact with the XRCC4 x DNA-ligase IV complex and is implicated in the DNA religation step of the NHEJ pathway.