NLRP2 Antikörper (AA 704-754)

Produktnummer ABIN7448989

Produktdetails anti-NLRP2 Antikörper

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Bindungsspezifität: AA 704-754

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Verwendungszweck: Rabbit anti-NBS1 IHC Antibody, affinity purified

Homologie: Orangutan,Monkey,Gorilla,Chimpanzee,Olive baboon,Crab-eating macaque,Bornean orangutan,Primates,Angolan talapoin,Francois's leaf monkey,Northern white-cheeked gibbon,Agile gibbon,Siamang,Black-and-white colobus monkey

Aufreinigung: Affinity Purified

Immunogen: Between AA 704 and 754

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu NLRP2

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Andere Bezeichnung: NBS1 (NLRP2 Produkte)

Hintergrund: Background: Mutations in NBS1 (Nijmegen Breakage Syndrome 1), also known as nibrin, are associated with the autosomal recessive syndrome, Nijmegen breakage syndrome, characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. At the cellular level, NBS1 is part of the MRE11/RAD50 double-strand break repair complex that is critical to the DNA damage response, DNA recombination, telomere integrity, and cell cycle checkpoint control.

Gen-ID: 4683

NCBI Accession: NP_002476

UniProt: O60934

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome