UBR4 Antikörper (AA 5133-5183)

Produktnummer ABIN7448995

Produktdetails anti-UBR4 Antikörper

Target: UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))

Bindungsspezifität: AA 5133-5183

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBR4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Verwendungszweck: Rabbit anti-p600 IHC Antibody, Affinity Purified

Homologie: Mouse,Rat,Horse,Pig,Orangutan,Monkey,Gorilla,Chimpanzee,Little brown bat,Northern white-cheeked gibbon,White-tufted-ear marmoset

Aufreinigung: Affinity Purified

Immunogen: Between AA 5133 and 5183

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu UBR4

Target: UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))

Andere Bezeichnung: p600 (UBR4 Produkte)

Synonyme: ZUBR1 antikoerper, RBAF600 antikoerper, p600 antikoerper, 1810009A16Rik antikoerper, A930005E13Rik antikoerper, D930005K06Rik antikoerper, Gm1032 antikoerper, Gm1666 antikoerper, N28143 antikoerper, Zubr1 antikoerper, mKIAA0462 antikoerper, Rbaf600 antikoerper, ubiquitin protein ligase E3 component n-recognin 4 antikoerper, E3 ubiquitin-protein ligase UBR4 antikoerper, UBR4 antikoerper, Ubr4 antikoerper, LOC100511934 antikoerper

Hintergrund: Background: p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions [taken from the Universal Protein Resource (UniProt) Q5T4S7].

Gen-ID: 23352

NCBI Accession: NP_065816

UniProt: Q5T4S7